IL1-beta-receptor antagonist

Anakinra/Kineret, peptid

  Inhibitors of excessive inflammation during infection

Interleukin-1 receptor inhibits an important signaling agent that controls the immune system’s quality in infections

Bacteria activate IL-1 production in human cells

Urinary bladder pathology

Acute cystitis is caused by bacteria that trigger exaggerated IL-1 responses

Bacteria (green) and inflammatory cells (red)

Therapeutic intervention

IL1-beta receptor inhibition in a murine infection model

Clinical relevance of IL-1 as a diagnostic biomarker in patient samples