Exciting research projects and novel therapies
Infections continue to threaten human health as pathogenic organisms outsmart available therapies with remarkable genetic versatility. Fortunately, microbial versatility is matched by the flexibility of the host immune system, which provides a rich source of novel therapeutic concepts.
Our therapeutic strategy is to find and develop substances that strengthen the immune system. Rather than drugs killing the bacteria directly the patient’s immune system is empowered to deal with the bacteria.
Our goal is to provide a different molecular framework for the treatment of bacterial infections; much needed to combat antibiotic resistance.
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IRF7 inhibition prevents destructive innate immunity—A target for nonantibiotic therapy of bacterial infections
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Ambite, I. et al. PLoS Pathogens 12, e1005848, doi:10.1371/journal.ppat.1005848 (2016).